Publications

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Dr. Wosnitzer, a leading urologist and male reproductive medicine expert in Connecticut, has published and presented extensively on vasectomy reversal, male infertility, erectile and sexual dysfunction, and urology topics.  Dr. Wosnitzer regularly lectures internationally on his research involving both clinical studies and basic science laboratory research studies of genetics and men’s health.

Recent article and book publications of importance to the field (in chronological order):

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Selected Peer-reviewed Publications:

Shahara, F. et al. Wosnitzer M.  Multicentric, prospective observational data show sperm capacitation predicts male fertility, and cohort comparison reveals a high prevalence of impaired capacitation in men questioning their fertility. Reprod Biomed Online. 2020 Jul;41(1):69-79. doi: 10.1016/j.rbmo.2020.03.011. Epub 2020 May 1.PMID: 32505543

Stawiarski K, Wosnitzer M, Erben Y.  A novel hybrid left renal vein transposition and endovascular stenting technique for the treatment of posterior nutcracker syndrome.  J Vasc Surg Cases Innov Tech. 2017 Jul 18;3(3):142-145. doi: 10.1016/j.jvscit.2017.04.003. eCollection 2017 Sep.PMID: 32505543

O’Rourke TK Jr, Erbella A, Zhang Y, Wosnitzer MS.  Prevention, identification, and management of post-operative penile implant complications of infection, hematoma, and device malfunction.  Transl Androl Urol. 2017 Nov;6(Suppl 5):S832-S848. doi: 10.21037/tau.2017.06.07.

O’Rourke, T, Wosnitzer MS.  Opioid-induced Androgen Deficiency (OPIAD): Diagnosis, Management, and Literature Review.  Current Urology Reports.  Volume 17, 2016.PMID: 32505543

Dabaja AA, Mielnik A, Robinson BD, Wosnitzer MS et al. Possible germ cell-Sertoli cell interactions are critical for establishing appropriate expression levels for the Sertoli cell-specific MicroRNA, miR-202-5p, in human testis.  Basic Clin Androl. 2015 Mar 3;25:2. doi: 10.1186/s12610-015-0018-z. eCollection 2015.PMID: 32505543

Wosnitzer MS, Mielnik A, Dabaja AA, Robinson B, Schlegel PN, Paduch DA. Ubiquitin Specific Protease 26 (USP26) Expression Analysis in Human Testicular and Extragonadal Tissues Indicates Diverse Action of USP26 in Cell Differentiation and Tumorigenesis. PLOS One. 6/2014.

Wosnitzer MS, Goldstein M. Azoospermia: Review of non-obstructive and obstructive azoospermia. Spermatogenesis. 3/2014.

Meyer A, Ghandour R, Bergman A, Castaneda C, Wosnitzer MS, Hruby G, Benson M, McKiernan J. The Natural History of Clinical Complete Responders Following Neoadjuvant Chemotherapy for Urothelial Carcinoma of the Bladder. Journal of Urology. 3/2014.

Dabaja AA, Wosnitzer MS, Mielnik A, Bolyakov A, Schlegel PN, Paduch DA.  Bulbocavernosus muscle area measurement: a novel method to assess androgenic activity.  Asian J Androl. 2/2014.

Wosnitzer MS. Genetics of male infertility. Translational Andrology and Urology, 3/2014.

Dabaja A, Wosnitzer MS, Bolyakov A, Schlegel PN, Paduch DA. When to ask male adolescents to provide semen sample for fertility preservation? Translational Andrology and Urology. 3/2014

Wosnitzer MS, Zhao F, Li P.  Update of genetic evaluation of azoospermia. National Journal of Andrology, China.  20(1). 1/2014.

Wosnitzer MS, Goldstein M.  Obstructive Azoospermia.  Review Article. Urologic Clinics of North America. 5/2013.

Wosnitzer MS, Dabaja A, Goldstein M. Varicocele and Hypogonadism.  Review Article. Current Urology Reports. Volume 14, Issue 4, 4/2013.

Wosnitzer MS, Paduch DA.  Endocrinological issues and hormonal manipulation in children and men with Klinefelter Syndrome.  American Journal of Medical Genetics Part C: Seminars in Medical Genetics. Epub 2013 Jan 18.

Yeschina O, Badalato GM, Wosnitzer MS, Hruby G, Roychoudhury A, Benson MC, Petrylak DP, McKiernan JM.  Relative efficacy of perioperative gemcitabine and cisplatin versus methotrexate, vinblastine, adriamycin, and cisplatin in the management of locally advanced urothelial carcinoma of the bladder.  Urology.  2012 Feb;79(2):384-90. Epub 2011 Dec 22.

Wosnitzer MS, Hruby GW, Murphy AM, Barlow LJ, Cordon-Cardo C, Petrylak DP, Benson MC, McKiernan JM.  A comparison of the outcomes of neoadjuvant and adjuvant chemotherapy for clinical T2-T4aN0-N2M0 bladder cancer. 2012 Jan 15;118(2):358-64.

Badalato, GM, Wosnitzer MS, Truesdale MD, Sandri M, Ko WJ, Landman J, Badani KK.Evaluation of preoperative bioimpedance spectroscopy quantification of body composition on predicting postoperative outcomes following robotic assisted radical prostatectomy (RARP). Can J Urol. 2011 Dec;18(6): 6031-6.

Sprenkle PC, Badalato GM, Wosnitzer MS, McKiernan JM, Parravicini E, Bagiella E, Goluboff ET, Benson MC, Rutman MP.  Exploring medical student education initiatives: does the management of urologic conditions improve with a formal urology clinical clerkship? Journal of Medicine and the Person.  2011; 9(3): 116-122. DOI: 10.1007/s12682-011-0101-y.

Wosnitzer MS, Domingo-Domenech J,  Castillo-Martin M, Petrylak DP, Benson MC, McKiernan JM, Cordon-Cardo C. Predictive value of microtubule associated proteins tau and stathmin in patients with non-muscle invasive bladder cancer receiving adjuvant intravesical taxane therapy. Journal of Urology. 2011 Nov;186(5):2094-100.

Wosnitzer MS, Greenfield JM. Antibiotic patterns with inflatable penile prosthesis insertion.Journal of Sexual Medicine.  2011 May;8(5):1521-8.

Wosnitzer MS, Hruby G, Sissi H, Benson MC, McKiernan JM. Role of preoperative platelet level in clinical and pathological outcomes after surgery for renal cortical malignancies. British Journal of Urology. 2011 Jul;108(1):73-9.

Wosnitzer MS and FC Lowe.  Management of prostate cancer in HIV-positive patients.Nature Reviews Urology. Nature Reviews Urology. 2010 Jun;7(6):348-57

Wosnitzer MS and Rutman MP.  KTP/LBO laser vaporization of the prostate.  Urol Clin North Am. 2009 Nov;36(4):471-83, vi.

Wosnitzer MS, Walsh R, Rutman MP.  The use of sacral nuromodulation for the treatment of non-obstructive urinary retention secondary to Guillain-Barré Syndrome. International Journal of Urogynecology.  2009. Sep;20(9):1145-7.

Wosnitzer MS, Xavier K, Gupta M. Novel use of a ureteroscopic stone entrapment device to prevent antegrade stone migration during percutaneous nephrolithotomy. J. Endourology, 2009. Feb;23(2):203-7.

DeJusta DG, Wosnitzer MS, Barone JG.  Persistent motor deficits predict long-term bladder dysfunction in children following acute transverse myelitis.  Journal of Urology.  2008. Oct: 180: 1774-1777.

Pierorazio PM, Kinnaman MD, Wosnitzer MS, Benson MC, McKiernan JM, Goluboff ET.Prostate volume and pathologic prostate cancer outcomes after radical prostatectomy.  Urology. 2007. Oct;70(4):696-701.

Ross MJ, Wosnitzer MS, Ross MD, Granelli B, Gusella GL, Husain M, Kaufman L, Vasievich M, D’Agati VD, Wilson PD, Klotman ME, Klotman PE. Role of ubiquitin-like protein FAT10 in epithelial apoptosis in renal disease.  J Am Soc Nephrol. 2006 Apr;17(4):996-1004. Epub 2006 Feb22.

Wosnitzer MS and Weiss RE.  Diagnosing and Managing Prostatic Abscess: Views from the Literature.  And Prostatitis or Prostatic Abscess?  Issues in Urology.  Vol.19 No.3.  May/June 2007.

Wosnitzer MS, Shusterman D, Barone JG. Bladder rupture in a pre-mature infant during a voiding cystourethrogram. Urology. 2005. Aug;66(2):432.
 
 
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Book Chapters:

Wosnitzer MS, Dabaja A, Schlegel PN. Endocrine Therapy for Male Infertility. AUA Update Series 2014, Volume 33, Lesson 4, American Urological Association.

Wosnitzer MS, Ahn JJ, and Lowe FC. Tewari, A.  Prostate Cancer: A Comprehensive Perspective.  HIV and Prostate Cancer. Springer, 2013.

Wosnitzer MS, and Goluboff ET.  Patient Surveillance after Cancer Treatment. Book Chapter: 24, Springer, 2012.

Wosnitzer MS, and Benson MC.  Netter Urinary System, 2nd edition, (Volume 5 in the Netter Collection of Medical Illustrations Series):  Bladder Cancer, Upper Urinary Tract Tumors, and Surgical Treatment of Bladder Cancer.  Elsevier, 2012. Plates 9:9-9:13.

Wosnitzer MS, and Fisch H. Effect of Advanced Age on Male Infertility: Chapter 7.  Biennial Review of Reproduction.  1st Edition.  Springer, 5/2009.

Abstracts/Moderated Posters/Podium Presentations/News Articles:

Wosnitzer MS, Goldstein M. Preoperative Ultrasound Varicocele Vein Diameter Underestimates Intraoperative Assessment.  ASRM Annual Meeting, Moderated Poster, 10/2014.

Lee D, Wosnitzer MS, Paduch DA. Influence of Clomiphene Citrate on BMI and Cholesterol Levels in the Treatment of Hypogonadism.  ASRM Annual Meeting, Moderated Poster, 10/2014.

Wosnitzer MS, Mielnik A, Dabaja A, Robinson B, Schlegel PN, Paduch DA. hUSP26 Expression in Human Testis and Relationship to Sperm Retrieval Outcome. AUA Annual Meeting, Moderated Poster, 5/2014.

Dabaja A, Mielnik A, Wosnitzer MS, Schlegel PN, Paduch DA. MicroRNA Expression in Normal and Abnormal Testis Histology. AUA Annual Meeting, Moderated Poster, 5/2014.

Wosnitzer MS, Mielnik A, Dabaja A, Robinson B, Schlegel PN, Paduch DA. hUSP26 Expression and Relationship to Androgen Receptor in Normal Human Testis. ASA Annual Meeting, Moderated Poster, 4/2014.

Dabaja A, Mielnik A, Wosnitzer MS, Schlegel PN, Paduch DA. MicroRNA Expression in Men with Confirmed Diagnosis of early maturation arrest. ASA Annual Meeting, Podium Presentation, 4/2014.

Wosnitzer MS, Goldstein M. Relationship of Sperm Granuloma to Obstructive Interval and Vasectomy Reversal Patency Outcomes. ASRM Annual Meeting, Moderated Poster, 10/2013.

Wosnitzer MS, Dabja A, Schlegel PN, Paduch DA. Role of Estradiol, Prolactin, and Inhibin B in Ejaculation. ASRM Annual Meeting, Moderated Poster, 10/2013.

Dabaja A, Mehta A, Wosnitzer MS, Goldstein M. Microsurigcal Hydrocelectomy. ASRM Annual Meeting, Moderated Poster, 10/2013.

Dabaja A, Mehta A, Wosnitzer MS, Goldstein M. Microdot Vasovasostomy Improves Patency and Timing to Return of Sperm to Ejaculate. ASRM Annual Meeting, Moderated Poster, 10/2013.

Wosnitzer MS, Dabaja A, Bolyakov A, Schlegel PN, Paduch DA. Testosterone, LH, FSH, and SHBG in normal male ejaculatory function. AUA Annual Meeting, Podium Presentation, 5/2013.

Wosnitzer MS, Dabaja A, Bolyakov A, Schlegel PN, Paduch DA. Down-regulation of hUSP26 in Hormonally-Receptive Cancers Suggests a Role in Cancer Development. AUA Annual Meeting, Moderated Poster, 5/2013.

Wosnitzer MS, Dabaja A, Bolyakov A, Schlegel PN, Paduch DA. Deletion and Mutation Analysis of Recombination Genes in Men with Meiotic Defects. AUA Annual Meeting, Moderated Poster, 5/2013.

Wosnitzer MS, Dabaja A, Bolyakov A, Paduch DA, Schlegel PN. DHEA and DHEA-S in Normal Male Ejaculatory Function. ASA Annual Meeting, Moderated Poster, 3/2013.

Wosnitzer MS, Dabaja A, Bolyakov A, Paduch DA. The Role of Serotonin, Dopamine, Epinephrine, and Norepinephrine in Normal Male Ejaculation. ASA Annual Meeting, Moderated Poster, 3/2013.

Wosnitzer MS, Dabaja A, Bolyakov A, Paduch DA. The Role of Oxytocin in Normal Male Ejaculatory Function. American Society of Andrology (ASA) Annual Meeting, Moderated Poster, 3/2013.

Dabaja A, Wosnitzer MS, Bolyakov A, Paduch DA. Does Increased Age Decrease Orgasm? American Society of Andrology (ASA) Annual Meeting, Moderated Poster, 3/2013.

Wosnitzer MS. Opioid-induced Androgen Deficiency and Obesity-related Hypogonadism. Eli Lilly/Weill Cornell Medical College Symposium, Invited Speaker, 11/2012.

Wosnitzer MS, Hruby GH, Cordon-Cardo C, Benson MC, Petrylak DP, McKiernan JM. Carboplatin versus Cisplatin-based Chemotherapy in the Perioperative Treatment of Muscle-Invasive Bladder Cancer. AUA Annual Meeting, Moderated Poster, 6/2010.

Wosnitzer MS, Hruby GH, Barlow L, Cordon-Cardo C, Benson MC, Petrylak DP, McKiernan JM. Systemic Chemotherapy Regimen for Bladder Cancer and Influence on Outcomes in Neoadjuvant and Adjuvant Settings. AUA Annual Meeting, Moderated Poster, 6/2010.

Wosnitzer, MS. Reception versus Conception. The Daily, News Corporation. September, 20, 2011. http://www.thedaily.com/page/2011/09/20/092011-arts-health-mobiles-male-fertility-1-2/

Wosnitzer MS, Rothberg M, Katsumi H, Gupta M. Efficacy of Novel Coaxial Occlusion Device to Prevent Stone Migration During Percutaneous Nephrolithotomy (PCNL). AUA Annual Meeting, Podium Presentation, 6/2/2010.

Wosnitzer MS, Truesdale MD, Sartori S, Ko WJ, Sandri M, Haramis G, Landman J, and KK Badani. Evaluation of Preoperative Bioimpedance Spectroscopy Quantification of Body Composition in Patients Prior to Robotic-assisted Radical Prostatectomy (RARP). World Congress Endourology, Moderated Poster, 10/2010.

Truesdale MD, Ko WJ, Hruby GW, Wosnitzer MS, Landman J, and KK Badani. A Comparison of Time to Recovery of Erectile Function Following Robotic-Assisted Radical Prostatectomy (RARP) Based on Nerve

Preservation Technique Used: Factors Associated with Speed of Recovery. World Congress of Endourology, Moderated Poster, 10/2010.

Wosnitzer MS and Greenfield JM. Antibiotic Patterns Among Urologists Who Perform Inflatable Penile Prosthesis Insertion. Sexual Medicine Society of North America (SMSNA) Annual Meeting, Podium Presentation #22, 11/2009.

Wosnitzer MS, Barlow L, Woldu S, Hruby GH, Cordon-Cardo C, Petrylak DP, Benson MC, McKiernan JM. Results of Bladder Preservation after “Neoadjuvant” Chemotherapy in Patients with Clinical Complete Response to Platinum-based Chemotherapy for Muscle-invasive Bladder TCC. Society of Urologic Oncology (SUO) Annual Meeting, Moderated Poster, 12/2009.

Wosnitzer MS, Rothberg M, Katsumi H, Gupta M. Efficacy of Novel Coaxial Occlusion Device to Prevent Stone Migration During Percutaneous Nephrolithotomy (PCNL). World Congress Endourology, Moderated Poster, 10/2009.

Wosnitzer MS, Rothberg M, Katsumi H, Gupta M. Novel Use of a Coaxial Film-based Occlusion Device for Optimal Access During Percutaneous Nephrolithotomy. World Congress Endourology, Moderated Poster, 10/2009.

Wosnitzer MS, Lee DJ, Hirsh AJ, JM McKiernan. Predictors of Renal Function in Nephron Sparing Surgery for Renal Cell Carcinoma in Solitary Kidneys. J Clinical Oncology. 27, 2009 (supplement e16045). ASCO 2009.

Wosnitzer MS, Kathrins M, Hruby G, Hirsh AJ, Desai M, Benson MC, McKiernan JM. The Role of Preoperative Platelet Level in Renal Surgical Outcomes. AUA Annual Meeting, Moderated Poster, 4/2009.

Wosnitzer MS, Xavier K, Gupta M. Novel Use of a Ureteroscopic Stone Entrapment Device to Prevent Antegrade Stone Migration During Percutaneous Nephrolithotomy. World Congress of Endourology, Moderated Poster, 11/2008.

Pierorazio PM, Kinnaman MD, Wosnitzer MS, Benson MC, McKiernan JM, Goluboff ET. Prostate Volume and Pathologic Prostate Cancer Outcomes After Radical Prostatectomy. AUA Annual Meeting, Moderated Poster, 5/2007.

McCann TR, Wosnitzer MS, McKiernan JM, Benson MC, Olsson CA, Goluboff ET. Risk of Disparity Between Needle Biopsy and Final Pathologic Gleason Score is not Correlated with Prostate Volume. AUA Annual Meeting, Moderated Poster, 5/2006.

Ross MJ, Ross MD, Wosnitzer MS, et al. Role of the Ubiquitin-like Protein FAT10 in Epithelial Apoptosis in Renal Disease. American Society of Nephrology Annual Meeting, Moderated Poster, 11/2005.

Wosnitzer MS, Klotman PE, Ross MJ. The Proapoptotic Protein FAT10 Localizes to Mitochondria and Nuclei in Renal Epithelial Cells. American Society of Nephrology Annual Meeting, Moderated Poster, 11/2005.